Ocular surface squamous neoplasia – Review of etio-pathogenesis and an update on clinico-pathological diagnosis
نویسندگان
چکیده
منابع مشابه
Ocular Surface Squamous Neoplasia
The ocular surface is composed of the conjunctiva and the cornea. The conjunctiva is a mucous membrane which covers the globe and inner part of the eyelids. The morphology of conjunctival epithelial cells are nonkeratinized stratified epithelia which vary from cuboidal over the tarsus, to columnar in the fornices, to squamous epithelia on the globe. Goblet cells account for up to 10% of the bas...
متن کاملupdates on diagnosis and treatment of ocular surface squamous neoplasia (ossn)
ocular surface may be involved by different neoplastic lesions ranging from benign to highly malignant. recognition of risk factors, clinical presentations, pathology, and different therapeutic modalities is essential for selecting an appropriate approach. this article deals with the proper approach to ocular surface squamous neoplasia (ossn) including conjunctival/corneal intraepithelial neopl...
متن کاملUltraviolet radiation and the role of matrix metalloproteinases in the pathogenesis of ocular surface squamous neoplasia.
PURPOSE Ocular surface squamous neoplasia (OSSN) is an uncommon tumor of the corneal and conjunctival epithelium associated with risk of permanent visual impairment. The purposes of this study were to (1) identify and localize potential mediators in tissue from patients with OSSN and (2) culture human dysplastic conjunctival epithelial cells (DCECs) to determine their responsiveness to ultravio...
متن کاملtopical mitomycin c for partially excised ocular surface squamous neoplasia
purpose : to develop a guideline for the treatment of incompletely removed histopathologically documented ocular surface neoplasia (ossn) with mitomycin c (mmc). materials & methods : through an interventional case series, 17 eyes of 17 patients presented with incompletely removed ossn were treated according to a protocol using 2-3 alternate 7-day courses of mmc 0.04%. clinical recurrence was r...
متن کاملEpidemiology of ocular surface squamous neoplasia in Africa
OBJECTIVES To describe the epidemiology and an aetiological model of ocular surface squamous neoplasia (OSSN) in Africa. METHODS Systematic and non-systematic review methods were used. Incidence was obtained from the International Agency for Research on Cancer. We searched PubMed, EMBASE, Web of Science and the reference lists of articles retrieved. Meta-analyses were conducted using a fixed-...
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ژورنال
عنوان ژورنال: Saudi Journal of Ophthalmology
سال: 2013
ISSN: 1319-4534
DOI: 10.1016/j.sjopt.2013.07.002